Japanese

Naoki Takeishi

PhD of Biomedical Engineering

Associate Professor

Kyushu University

Department of Mechanical Engineering

Biofunctional Engineering Laboratory

Email: takeishi.naoki.008_at_kyushu-u.ac.jp


Summary

I am an associate professor working in Kyoto Institute of Technology, Japan. My research interests are complex fluid especially in the body (e.g., microcirculatory blood flow, interstitial flow, and etc), computational biomechanics, and GPU computing.


* denotes corresponding author

Publications

    Journal articles

  1. Spatiotemporal distribution of YAP and importin-β in nucleus and cytosol after wounding of adjacent cells.
    Boyuan Xiao, Saori, Sasaki, Naoki Takeishi, Toshihiro Sera, Susumu Kudo∗. In Vitro Cell. Dev. Biol.-Anim. 2025. Accepted.

  2. Phase changes of the flow rate in the vertebral artery caused by debranching thoracic endovascular aortic repair: effects of flow path and local vessel stiffness on vertebral arterial pulsation.
    Naoki Takeishi∗, Li Jialong, Naoto Yokoyama, Hisashi Tanaka, Takasumi Goto, Shigeo Wada. Med. Eng. Phys. 2025, 140:104348.

  3. Inertial focusing of spherical capsule in pulsatile channel flows.
    Naoki Takeishi∗, Kenta Ishimoto, Naoto Yokoyama, Marco E. Rosti∗. J. Fluid Mech. 2025, 1008:A46.

  4. Spatiotemporal distribution of PKCα, PIP3, Moesin, Cdc42, MARCKS, Scriblle, and Arf6 before directed cell migration in monolayers.
    Quanzhi Lu, Katsuyuki Ushijima, Saori, Sasaki, Toshihiro Sera, Naoki Takeishi, Susumu Kudo∗. Biochem. Biophys. Res. Commun. 2025, 750:151371, https://doi.org/10.1016/j.bbrc.2025.151371.

  5. Microscale topographies on biomaterial surfaces modulate cell migration.
    Saori Sasaki∗, Keita Eguchi, Ming Wei, Ryu Takahashi, Toshihiro Sera, Naoki Takeishi, Susumu Kudo∗. J. Biorheol. 2024, 38:120-125, https://doi.org/10.17106/jbr.38.120.

  6. Quantification of membrane protein diffusion on endothelial cell surfaces under shear stress using a photochromic fluorescent protein.
    Naoto Kawasaki, Keita Hamasaki, Saori Sasaki, Naoki Takeishi∗, Susumu Kudo∗. J. Biorheol. 2024, 38:88-93, https://doi.org/10.17106/jbr.38.88.

  7. Numerical-experimental estimation of the deformability of human red blood cells from rheometrical data.
    Naoki Takeishi∗, Tomohiro Nishiyama, Kodai Nagaishi, Takeshi Nashima, Masako Sugihara-Seki. J. Rheol. 2024, 68:837-848, https://doi.org/10.1122/8.0000877

  8. Construction of multilayered small intestine-like tissue by reproducing interstitial flow.
    Sayaka Deguchi∗, Kaori Kosugi, Naoki Takeishi, Yukio Watanabe, Shiho Morimoto, Ryosuke Negoro, Fuki Yokoi, Hiroki Futatsusako, May Nakajima-Koyama, Mio Iwasaki, Takuya Yamamoto, Yoshiya Kawaguchi, Yu-suke Torisawa, Kazuo Takayama∗. Cell Stem Cell. 2024, 31:1-12, https://doi.org/10.1016/j.stem.2024.06.012.

  9. Numerical analysis of viscoelasticity of two-dimensional fluid membranes under oscillatory loadings.
    Naoki Takeishi∗, Masaya Santo, Naoto Yokoyama, Shigeo Wada. Results Eng. 2024, 22:102304, https://doi.org/10.1016/j.rineng.2024.102304.

  10. Viscoelasticity of suspension of red blood cells under oscillatory shear flow.
    Naoki Takeishi∗, Marco E. Rosti, Naoto Yokoyama, Luca Brandt. Phys. Fluids 2024, 36:041905, https://doi.org/10.1063/5.0196272.

  11. Enhanced axial migration of a deformable capsule in pulsatile channel flows.
    Naoki Takeishi∗, Marco E. Rosti∗. Phys. Rev. Fluids 2023, 8:L061101, https://doi.org/10.1103/PhysRevFluids.8.L061101.

  12. Inertial migration of red blood cells under a Newtonian fluid in a circular channel.
    Naoki Takeishi∗, Hiroshi Yamashita, Toshihiro Omori, Naoto Yokoyama, Shigeo Wada, Masako Sugihara-Seki. J. Fluid. Mech. 2022, 952:A35, https://doi.org/10.1017/jfm.2022.936.

  13. Computational fluid dynamics assessment of congenital tracheal stenosis.
    Keiichi Morita∗, Naoki Takeishi, Shigeo Wada, Tadashi Hatakeyama. Pediatr. Surg. Int. 2022, 38:1769-1776, https://doi.org/10.1007/s00383-022-05228-6.

  14. Fluid dynamic assessment of positive end-expiratory pressure in a tracheostomy tube connector during respiration.
    Shiori Kageyama, Naoki Takeishi∗, Hiroki Taenaka, Takeshi Yoshida, Shigeo Wada. Med. Biol. Eng. Comput. 2022, 60:2981-2993, https://doi.org/10.1007/s11517-022-02649-2.

  15. Airway performance in infants with congenital tracheal stenosis associated with unilateral pulmonary agenesis: effect of tracheal shape on energy flux.
    Shiori Kageyama, Naoki Takeishi∗, Naoki Harada, Kao Taniguchi, Keiichi Morita, Shigeo Wada. Med. Biol. Eng. Comput. 2022, 60:2335-2348, https://doi.org/10.1007/s11517-022-02601-4.

  16. Assessment of cardiac function using modified ejection fraction as an indicator of myocardial circumferential strain.
    Takaomi Morishita∗, Naoki Takeishi, Satoshi Ii, Shigeo Wada. J. Biomech. Sci. Eng. 2022, 17(2):22-00014, https://doi.org/10.1299/jbse.22-00014.

  17. Development of a mesoscopic framework spanning nanoscale protofibril dynamics to macro-scale fibrin clot formation.
    Naoki Takeishi, Taiki Shigematsu, Ryogo Enosaki, Shunichi Ishida, Satoshi Ii∗, Shigeo Wada. J. R. Soc. Interface. 2021, 18(184):20210554, https://doi.org/10.1098/rsif.2021.0554.

  18. Axial and nonaxial migration of red blood cells in a microtube.
    Naoki Takeishi∗, Hiroshi Yamashita, Toshihiro Omori, Naoto Yokoyama, Masako Sugihara-Seki. Micromachines. 2021, 12(10):1162, https://doi.org/10.3390/mi12101162.

  19. Cerebrospinal fluid flow driven by arterial pulsations in axisymmetric perivascular spaces: analogy with Taylor's swimming sheet.
    Naoto Yokoyama∗, Naoki Takeishi, Shigeo Wada. J. Theol. Biol. 2021, 523:110709, https://doi.org/10.1016/j.jtbi.2021.110709.

  20. Effects of left ventricular hypertrophy and myocardial stiffness on myocardial strain under preserved ejection fraction.
    Takaomi Morishita, Naoki Takeishi, Satoshi Ii, Shigeo Wada∗. Ann. Biomed. Eng. 2021, 49:1670–1687, https://doi.org/10.1007/s10439-020-02706-7.

  21. Haemorheology in dilute, semi-dilute and dense suspensions of red blood cells.
    Naoki Takeishi∗, Marco E. Rosti, Yohsuke Imai, Shigeo Wada, Luca Brandt. J. Fluid. Mech. 2019, 872:818-848, https://doi.org/10.1017/jfm.2019.393.

  22. Capture event of platelets by bolus flow of red blood cells in capillaries.
    Naoki Takeishi∗, Yohsuke Imai, Shigeo Wada. J. Biomech. Sci. Eng. 2019, 14(3):18-00535, https://doi.org/10.1299/jbse.18-00535.

  23. Deformation of a red blood cell in a narrow rectangular microchannel.
    Naoki Takeishi∗, Hiroaki Ito, Makoto Kaneko, Shigeo Wada. Micromachines 2019, 10(3):199, https://doi.org/10.3390/mi10030199.

  24. Fluid dynamic assessment of tracheal flow in infants with congenital tracheal stenosis before and after surgery.
    Naoki Takeishi, Tomohiro Miki, Tomohito Otani, Satoshi Ii, Keiichi Morita, Shigeo Wada∗. Med. Biol. Eng. Comput. 2019, 57:837-847, https://doi.org/10.1007/s11517-018-1928-7.

  25. Capture of microparticles by bolus flow of red blood cells in capillaries.
    Naoki Takeishi, Yohsuke Imai∗. Sci. Rep. 2017, 7:5381, https://doi.org/10.1038/s41598-017-05924-7.

  26. Cell adhesion during bullet motion in capillaries.
    Naoki Takeishi, Yohsuke Imai∗, Shunichi Ishida, Toshihiro Omori, Roger D. Kamm, Takuji Ishikawa. Am. J. Physiol .Heart & Circ. Physiol. 2016, 311(2):H395-H403, https://doi.org/10.1152/ajpheart.00241.2016.

  27. Flow of a circulating tumor cell and red blood cells in microvessels.
    Naoki Takeishi, Yohsuke Imai∗, Takami Yamaguchi, Takuji Ishikawa. Phys. Rev. E 2015, 92(6):063011, https://doi.org/10.1103/PhysRevE.92.063011.

  28. Leukocyte margination at arteriole shear rate.
    Naoki Takeishi, Yohsuke Imai∗, Keita Nakaaki, Takami Yamaguchi, Takuji Ishikawa. Physiol. Rep. 2014, 2(6):e12037, https://doi.org/10.14814/phy2.12037.

  29. A novel numerical scheme based on a porous media approach for prediction of local urban climatological phenomena.
    Fujio Kuwahara∗, Naoki Takeishi. Transactions of the Japan Society of Mechanical Engineers Series B (Japanese). 2011, 77(783):2181-2190, https://doi.org/10.1299/kikaib.77.2181.

    Peer-reviewed conference paper

  1. How to measure cellular shear modulus inside a chip: detailed correspondence to the fluid-structure coupling analysis.
    Hiroaki Ito∗, Naoki Takeishi, Atsushi Kirimoto, Misato Chimura, Tomohito Ohtani, Yasushi Sakata, Mitsuhiro Horade, Toshio Takayama, Makoto Kaneko. 2019 IEEE 32nd International Conference on Micro Electro Mechanical System (Seoul, Korea) 2019, doi:10.1109/MEMSYS.2019.8870772.

  2. Development of a numerical model for micro-scale blood flow simulation using GPGPU.
    Naoki Takeishi, Yohsuke Imai∗, Takuji Ishikawa, Takami Yamaguchi. ASME 2012 Summer Bioengineering Conference (Fajardo, Puerto Rico, USA). 2013, Paper No:SBC2012-80028, pp.823-824, doi:10.1115/SBC2012-80028.

    Japanese articles & MISC

    See Japanese site